{"id":43464,"date":"2025-06-13T16:33:37","date_gmt":"2025-06-13T16:33:37","guid":{"rendered":"https:\/\/momart.jowo.studio\/?p=43464"},"modified":"2026-05-15T09:22:59","modified_gmt":"2026-05-15T09:22:59","slug":"embriyolara-yapilan-genetik-testler","status":"publish","type":"post","link":"https:\/\/momart.com.tr\/en\/embriyolara-yapilan-genetik-testler\/","title":{"rendered":"Genetic Tests Performed on Embryos"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"43464\" class=\"elementor elementor-43464\">\n\t\t\t\t<div class=\"elementor-element elementor-element-40907b4 e-flex e-con-boxed cmsmasters-block-default e-con e-parent\" data-id=\"40907b4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-75c45e6 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-text-editor\" data-id=\"75c45e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"77\" data-end=\"432\">Genetic testing of embryos in in-vitro fertilization (IVF) treatments is a crucial step in increasing the chances of a healthy pregnancy and birth. These tests help detect potential genetic abnormalities in the embryo and select the healthiest embryos. However, it is important to understand the limitations of these tests and when they are necessary.<\/p><p data-start=\"434\" data-end=\"842\">Basic Information About Human Genetics<br data-start=\"472\" data-end=\"475\" \/>The human body contains 23 pairs of chromosomes, which carry our genetic makeup.<br data-start=\"541\" data-end=\"544\" \/>\u2022 22 pairs of autosomal chromosomes (not sex-related),<br data-start=\"601\" data-end=\"604\" \/>\u2022 One pair represents sex chromosomes (XX in women, XY in men).<br data-start=\"664\" data-end=\"667\" \/>Chromosomes contain approximately 30,000 genes. Changes in genes are called mutations. Some mutations are harmless, while others can lead to hereditary diseases.<\/p><p data-start=\"844\" data-end=\"1059\">Monosomy: The absence of one chromosome.<br data-start=\"882\" data-end=\"885\" \/>Trisomy: The presence of an extra chromosome (e.g., Down syndrome \u2013 Trisomy 21).<br data-start=\"959\" data-end=\"962\" \/>Modes of inheritance: Autosomal recessive, autosomal dominant, and X-linked inheritance.<\/p><p data-start=\"1061\" data-end=\"1123\">To date, more than 6,000 genetic diseases have been identified.<\/p><p data-start=\"1125\" data-end=\"1619\">In what situations are embryos genetically tested?<br data-start=\"1175\" data-end=\"1178\" \/>Genetic testing is not performed in every IVF treatment. However, genetic testing is recommended in the following situations:<br data-start=\"1273\" data-end=\"1276\" \/>\u2022 Consanguineous marriage and shared genetic carrier status,<br data-start=\"1323\" data-end=\"1326\" \/>\u2022 Previous history of pregnancy or child with genetic diseases,<br data-start=\"1383\" data-end=\"1386\" \/>\u2022 Known chromosomal abnormalities in women or men,<br data-start=\"1435\" data-end=\"1438\" \/>\u2022 Advanced age in women over 40,<br data-start=\"1474\" data-end=\"1477\" \/>\u2022 Recurrent miscarriages,<br data-start=\"1500\" data-end=\"1503\" \/>\u2022 Unsuccessful IVF attempts,<br data-start=\"1536\" data-end=\"1539\" \/>\u2022 When an HLA-matched sibling is planned for a child patient who needs a bone marrow transplant.<\/p><p data-start=\"1621\" data-end=\"2082\">Types of Genetic Tests<br data-start=\"1641\" data-end=\"1644\" \/>\u2022 <strong data-start=\"1646\" data-end=\"1700\">PGT-A (Preimplantation Genetic Test \u2013 Aneuploidy):<\/strong> It examines the chromosome number and structure of the embryo. It detects numerical abnormalities such as monosomy or trisomy.<br data-start=\"1811\" data-end=\"1814\" \/>\u2022 <strong data-start=\"1816\" data-end=\"1853\">PGT-M (Monogenic Disease Test):<\/strong> It is used in the research of single-gene diseases (e.g., SMA, thalassemia, cystic fibrosis).<br data-start=\"1947\" data-end=\"1950\" \/>\u2022 <strong data-start=\"1952\" data-end=\"1991\">PGT-SR (Structural Rearrangements):<\/strong> It is applied to couples with structural abnormalities in the chromosomes (translocation, inversion, etc.).<\/p><p data-start=\"2084\" data-end=\"2385\">Success Rate in Embryos with Chromosome Screening<br data-start=\"2136\" data-end=\"2139\" \/>Bilimsel veriler, tek bir genetik olarak normal embriyo (\u00f6ploid) transfer edildi\u011finde gebelik oran\u0131n\u0131n ortalama %70 oldu\u011funu g\u00f6stermektedir.<br data-start=\"2279\" data-end=\"2282\" \/>\u2022 3 transfer sonunda gebelik elde etme oran\u0131 %95,<br data-start=\"2331\" data-end=\"2334\" \/>\u2022 5 transfer sonunda ise %98\u2019e kadar \u00e7\u0131kmaktad\u0131r.<\/p><p data-start=\"2387\" data-end=\"2626\">Can all genetic diseases be screened for?<br data-start=\"2426\" data-end=\"2429\" \/>No. With current technologies, not all genetic diseases can be screened.<br data-start=\"2493\" data-end=\"2496\" \/>\u2022 <strong data-start=\"2498\" data-end=\"2531\">WES (Whole Exome Sequencing):<\/strong> It examines gene regions (exons) that code for proteins. However, the sensitivity of this test is limited.<\/p><p data-start=\"2628\" data-end=\"2754\">Therefore, if a known disease is present (e.g., SMA, thalassemia, cystic fibrosis), PGT-M provides much more reliable results.<\/p><p data-start=\"2756\" data-end=\"3040\">Does a normal test result guarantee a healthy baby?<br data-start=\"2805\" data-end=\"2808\" \/>No. Genetic tests have a margin of error. Here are the reasons:<br data-start=\"2870\" data-end=\"2873\" \/>\u2022 Technical limitations of the test,<br data-start=\"2904\" data-end=\"2907\" \/>\u2022 Studying only specific genetic domains,<br data-start=\"2954\" data-end=\"2957\" \/>\u2022 Mosaic embryos: Some cells in the embryo may be normal, while others may be abnormal.<\/p><p data-start=\"3042\" data-end=\"3356\">Are screening tests necessary during pregnancy with a tested embryo?<br data-start=\"3107\" data-end=\"3110\" \/>Yes. Even if the embryo has undergone genetic testing, routine screening tests should still be performed during pregnancy. Because embryo testing:<br data-start=\"3240\" data-end=\"3243\" \/>\u2022 It has a margin of error.,<br data-start=\"3269\" data-end=\"3272\" \/>\u2022 It can only show certain disorders,<br data-start=\"3315\" data-end=\"3318\" \/>\u2022 It does not cover all genetic diseases.<\/p><p data-start=\"3358\" data-end=\"3491\">Therefore, methods such as double and triple screening tests, detailed ultrasound, and amniocentesis if necessary, continue to be used during pregnancy.<\/p><p data-start=\"3493\" data-end=\"3826\">Conclusion<br data-start=\"3498\" data-end=\"3501\" \/>Genetic testing of embryos is an important technology that increases the success rate of in-vitro fertilization (IVF) treatment. However, it is important to know that these tests do not always eliminate all risks. Performing the correct test with the correct indication and ensuring that the expectant mother does not neglect standard screening tests throughout her pregnancy is the safest approach.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d7ff785 e-flex e-con-boxed cmsmasters-block-default e-con e-parent\" data-id=\"d7ff785\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>T\u00fcp bebek tedavilerinde embriyolara uygulanan genetik testler, sa\u011fl\u0131kl\u0131 gebelik ve do\u011fum \u015fans\u0131n\u0131 art\u0131rmak i\u00e7in \u00f6nemli bir a\u015famad\u0131r. Bu testler, embriyonun genetik yap\u0131s\u0131ndaki olas\u0131 bozukluklar\u0131n tespit edilmesine ve en sa\u011fl\u0131kl\u0131 embriyolar\u0131n se\u00e7ilmesine yard\u0131mc\u0131 olur. Ancak testlerin s\u0131n\u0131rlar\u0131n\u0131 ve hangi durumlarda gerekli olduklar\u0131n\u0131 bilmek \u00f6nemlidir. \u0130nsan Geneti\u011fi Hakk\u0131nda Temel Bilgiler\u0130nsan v\u00fccudunda genetik yap\u0131m\u0131z\u0131 ta\u015f\u0131yan 23 \u00e7ift kromozom&#8230;<\/p>","protected":false},"author":2,"featured_media":44386,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-43464","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Embriyolara Yap\u0131lan Genetik Testler - Momart T\u00fcp Bebek Merkezi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/momart.com.tr\/en\/embriyolara-yapilan-genetik-testler\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Embriyolara Yap\u0131lan Genetik Testler - Momart T\u00fcp Bebek Merkezi\" \/>\n<meta property=\"og:description\" content=\"T\u00fcp bebek tedavilerinde embriyolara uygulanan genetik testler, sa\u011fl\u0131kl\u0131 gebelik ve do\u011fum \u015fans\u0131n\u0131 art\u0131rmak i\u00e7in \u00f6nemli bir a\u015famad\u0131r. Bu testler, embriyonun genetik yap\u0131s\u0131ndaki olas\u0131 bozukluklar\u0131n tespit edilmesine ve en sa\u011fl\u0131kl\u0131 embriyolar\u0131n se\u00e7ilmesine yard\u0131mc\u0131 olur. 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Momart T\u00fcp Bebek Merkezi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/momart.com.tr\/en\/embriyolara-yapilan-genetik-testler\/","og_locale":"en_US","og_type":"article","og_title":"Embriyolara Yap\u0131lan Genetik Testler - Momart T\u00fcp Bebek Merkezi","og_description":"T\u00fcp bebek tedavilerinde embriyolara uygulanan genetik testler, sa\u011fl\u0131kl\u0131 gebelik ve do\u011fum \u015fans\u0131n\u0131 art\u0131rmak i\u00e7in \u00f6nemli bir a\u015famad\u0131r. Bu testler, embriyonun genetik yap\u0131s\u0131ndaki olas\u0131 bozukluklar\u0131n tespit edilmesine ve en sa\u011fl\u0131kl\u0131 embriyolar\u0131n se\u00e7ilmesine yard\u0131mc\u0131 olur. 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