PICSI, This is a microinjection (ICSI) method used in in vitro fertilization (IVF) treatment. In this method, sperm are placed in a special container. Picsi container It is selected with the help of. Unlike classic ICSI, sperm selection is based not only on motility and shape, but also on other factors. biological maturity is also taken into consideration.
What is the basic principle behind the PICSI method?
The base of the PICSI container, hyaluronic acid (HA) It is coated with a special hydrogel containing hyaluronic acid. Hyaluronic acid is a substance that occurs naturally in the body and is also naturally found around the egg cell. Only mature and healthy sperm can bind to this substance. Therefore, sperm that bind to HA:
- Their genetic material (DNA) is less damaged,
- Where fertilization potential is higher,
- It has been shown to yield more successful results in embryo development and pregnancy.,
This has been demonstrated by scientific research.
Who is PICSI suitable for?
- Couples experiencing recurrent IVF failure
- Recurrent pregnancy loss (miscarriages)
- Men with high sperm DNA damage
- Patients with morphologically normal sperm but of questionable genetic quality.
What is the purpose of PICSI?
🔹 By selecting healthier sperm improving embryo quality
🔹 In IVF to increase pregnancy rates
🔹 Low risk to reduce
🔹 Enabling fertilization with sperm that have low DNA damage healthy pregnancy to obtain
What is the difference between classic ICSI and PICSI?
Criterion | Classic ICSI | PICSI (Physiological ICSI) |
Sperm Selection Criteria | According to movement and morphology | Based on HA connectivity (biological maturity) |
DNA Damage Analysis | It is not directly evaluated. | Sperm with low DNA damage are preferred. |
Embryo Quality | Standard | It can create higher quality embryos. |
Application Area | All ICSI cases | Especially in cases of recurrent failure and miscarriage |
In conclusion
The PICSI method, in particular experiencing repeated failures or problems related to embryo quality were detectedIt is an effective option for couples. Thanks to this precise procedure performed in a laboratory environment, Sperm selection using a method that most closely resembles the mechanism of natural selection. It is provided.
At Momart IVF Center, we combine all advanced laboratory technologies, especially PICSI, with personalized treatment planning to determine the most suitable method to increase your chances of success.