Hyaluronic acid binding test (HBA test), sperm cells maturity and fertilization ability It is a specialized laboratory test for evaluation. The main purpose of the test is to identify high-quality and genetically healthier sperm.
How does the test work?
In the HBA test, sperm cells hyaluronic acid (HA) Its ability to bond to a specific surface is evaluated.
Hyaluronic acid is also found in the natural structures surrounding the female egg. Therefore, sperm that can bind to HA are more likely to mature., with a more robust DNA structure And it is considered to be more suitable for natural fertilization.
The ratio of the number of motile sperm that are attached to the number of motile sperm that are not attached is calculated during the test. HBA score It is calculated.
What does the HBA score mean?
- %80 ve üzeriSperm quality is quite good, fertilization potential is high.
- %60–80 arası: Acceptable level
- %60’ın altıLow percentage of mature sperm; further evaluation may be required.
Low scores can increase the risk of DNA damage and affect the success of in-vitro fertilization (IVF) or intrauterine microinjection (ICSI).
In what situations is an HBA test performed?
HBA testing is recommended in the following situations:
- ✅ Unexplained infertility
- ✅ Repeated IVF failures
- ✅ Low sperm morphology and motility
- ✅ Suspected sperm DNA damage
- ✅ Sperm selection before microinjection (ICSI)
What is its relationship with PICSI?
Sperm that pass the HBA test, Physiological ICSI (PICSI) This method can be used in microinjection. This technique allows for selection based on the natural binding abilities of sperm and can improve embryo quality.
HBA Test at Momart IVF Center
At Momart IVF Center, personalized approaches are offered according to the needs of couples, and the treatment process is supported with advanced analyses such as the HBA test. HBA test results play a crucial role in determining the treatment plan, especially for couples experiencing sperm-related problems.

